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Experts use weather to predict disease

Tue, 23 Jan 2007 14:21:17 GMT
By MARIA CHENG, AP Medical Writer
LONDON - Doctors hoping to predict disease outbreaks may want to tune into more weather forecasts.
Weather patterns can often be a key factor in finding out when an epidemic is imminent because they determine the conditions for germs and their carriers to breed.

The techniques can help quicken the response to viral outbreaks worldwide and health disasters like Europe's devastating 2003 heat wave — and global warming is adding urgency to such strategies for fighting disease.

Health officials were able to lessen the impact of an ongoing outbreak in Kenya of Rift Valley Fever, a deadly hemorrhagic fever, after NASA scientists noticed exceptionally warm sea temperatures and elevated rainfall in east Africa four months ago.

When flooding in Kenya started soon after, NASA climate expert Assaf Anyamba was certain the elements were in place for an outbreak — namely, ideal breeding conditions for the mosquitos that transmit the disease.

"By the end of October, this outbreak was pretty much a lock," he said.

Anyamba and his colleagues at NASA and other agencies track climatic factors that influence disease outbreaks, including levels of precipitation, atmospheric moisture, and vegetation.

This information is then passed to organizations including the World Health Organization and the Food and Agriculture Organization, which in turn relay it to the affected countries.

The last major outbreak occurred in Kenya in 1997, at exactly the same time of year, and killed approximately 400 people. The response was so slow that that by the time international experts landed in Kenya to fight the outbreak, it was already over.

This time around, the response was much quicker, partly due to the public health community's ability to predict the virus' arrival. Health officials flew to Kenya within days of the virus' confirmation in December, and the death toll has so far been limited to 104 people.

"Looking at the weather forecasting and satellite imaging data in November, we were already thinking, 'Rift,'" said Dr. Pierre Formenty, a WHO disease expert who was recently in Kenya to help contain the outbreak.

Once the Kenyan government was informed of the likelihood of an outbreak, they outlawed the sacrificing of cows, camels, goats and sheep during the Muslim Eid festival. That was done to minimize the contact between humans and infected animals, and is believed to have cut the risk factor for virus transmission to humans.

Rift Valley Fever is not the only disease affected by weather. Any disease spread by insects — such as malaria, yellow fever or encephalitis — is highly dependent on the conditions needed for the insects' survival, such as warm temperatures and plenty of water to breed.

Waterborne diseases such as cholera and typhoid are also particularly susceptible to weather changes.

Yet despite the established links between weather variability and disease outbreaks, global surveillance systems do not systematically monitor the weather.

"Some of my colleagues just laugh and tell me to open the window if I want to watch the weather," said Formenty.

One problem is that disease response systems are already so stretched in developing countries that adding weather to the list of things to watch won't necessarily help.

"We run the risk of just coming up with a very accurate warning system without having any capacity to actually respond," said Dr. Diarmid Campbell-Lendrum, a WHO climate change expert. "You can't solve malaria problems in Africa just by providing better risk information."
Even rich countries haven't entirely integrated weather considerations into their health surveillance systems. The heat wave that hit Europe in 2003, killing an estimated 15,000 people in France alone, was a reminder that the West is not immune to weather-related problems.
Global warming trends are likely to have disease consequences for the entire world. Unseasonably warm temperatures this year have already resulted in a spike of malaria and tick-borne encephalitis cases in Italy.
While climate change is likely to bring back tropical diseases to areas not used to them, weather is only one contributing factor.
"The prime determinant of whether or not a health risk translates into dead bodies is how well your public health system is functioning," Campbell-Lendrum said.
But when it comes fighting diseases like Rift Valley Fever, experts say any lead time is valuable.
"It gives us the chance to act before the outbreak instead of panicking during it," said Formenty, who helped Kenyan authorities prepare for an expected malaria outbreak by distributing bednets and bolstering supplies of anti-malarial drugs.

U.S. docs tough on blood pressure

Tue, 23 Jan 2007 04:10:09 GMT
By CARLA K. JOHNSON, Associated Press Writer
CHICAGO - High blood pressure is controlled better in the United States than in five Western European countries, a study found, and researchers credit American doctors' more aggressive prescribing of drugs.
The researchers pointed proudly to the findings, saying that the U.S. strategy of prescribing more pills earlier probably saves money overall by preventing heart attacks and strokes.

But other experts disputed that and questioned the cost-effectiveness of treating mildly high blood pressure.

The study was conducted by researchers at the University of Pennsylvania, University of Chicago and Stanford University and was published in Monday's Archives of Internal Medicine.

The researchers looked at doctors' reports on more than 21,000 patients treated for hypertension. They found that post-treatment blood pressure was 134 over 79 on average in the United States; 139/80 in France; 141/83 in Germany; 143/84 in Italy; 141/83 in Spain; and 144/82 in Britain.

A reading of 140/90 or above is considered high, both in America and abroad. High blood pressure raises the risk of a heart attack, stroke, heart failure and kidney failure.

The study also found that the use of more than one blood pressure drug per patient was highest in the United States, with 64 percent of the patients getting more than one class of drug. That compared with a low of 44 percent in Spain and 59 percent in Germany and Britain.

Study co-author Dr. Caleb Alexander of the University of Chicago said treating high blood pressure aggressively and early is "a good thing, given the burden of hypertension among the population."

High blood pressure affects more than 72 million adults in the United States, according to the http://www.archinternmed.com
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